Do Acid Sensing Ion Channels Contribute to Heartburn?

Summary

The purpose of this research study is to learn about whether treating the esophagus with amiloride reduces either the frequency or the time to onset of acid-induced heartburn in patients with nonerosive reflux disease. In particular, we are looking at people who have either had complete relief while using a Proton Pump Inhibitor (PPI) or who have only had some relief of symptoms while on a PPI.

Timeline

Start

2010-03

Primary completion

2011-09

Completion

2011-09

Drugs

Indications