drugset / Trial / NCT01095211
B-vitamins Treatment for Improvement of Cognitive Function
RandomizedParallel-groupTriple-blindPrevention
Summary
Observation studies documented a correlation between plasma concentrations of homocysteine and cognitive decline with age. The study hypothesis was that high doses of B-vitamins (as effective homocysteine lowering treatment) can improve cognitive function in elderly people.
Timeline
- Start
- 2003-01
- Primary completion
- 2005-09
- Completion
- 2009-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Pyridoxine | Unknown | 40 mg | Oral |
| Comparator | Vitamin B12 | Other / unclassified | 1 mg | Oral |
| Comparator | folic acid | Other / unclassified | 5 mg | Oral |