drugset / Trial / NCT01098409
Nitrite Mediated Cardioprotection During Coronary Artery Bypass Surgery
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to determine whether sodium nitrite administration 24 hours prior to or during coronary artery bypass surgery protects the heart better from lack of blood flow which occurs as part of this type of operation. The study will also determine what the mechanisms of this cardioprotection are.
Timeline
- Start
- 2010-02
- Primary completion
- 2012-01
- Completion
- 2012-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sodium Nitrite | Small molecule | 0.2 ug/kg | Intravenous |
| Subject | Sodium Nitrite | Small molecule | 1 ug/kg | Intravenous |
Indications
No indication recorded.