drugset / Trial / NCT01098747
Study Evaluating A Novel Ibuprofen Formulation In The Treatment Of Dental Pain
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This study will compare the pain relieving effect of a single-dose of a novel ibuprofen formulation to placebo and two formulations of standard ibuprofen in the treatment of post-surgical dental pain following "wisdom" tooth (third molar) removal.
Timeline
- Start
- 2010-04
- Primary completion
- 2010-07
- Completion
- 2010-08
Publications
- Jayawardena S, Leyva R, Kellstein D. Safety of a novel formulation of ibuprofen sodium compared with standard ibuprofen and placebo. Postgrad Med. 2015 Jan;127(1):33-7. doi: 10.1080/00325481.2015.993268. Epub 2014 Dec 15.
- Brain P, Leyva R, Doyle G, Kellstein D. Onset of analgesia and efficacy of ibuprofen sodium in postsurgical dental pain: a randomized, placebo-controlled study versus standard ibuprofen. Clin J Pain. 2015 May;31(5):444-50. doi: 10.1097/AJP.0000000000000142.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ibuprofen | Small molecule | 400 mg | — |
| Subject | Ibuprofen | Small molecule | 512 mg | — |
Indications
No indication recorded.