Evaluation of a Cincalcet Suppression Test

Summary

The aim of the study is to compare the results of a parathyroid hormone (PTH)suppression test using a single oral tablet of cinacalcet in two groups of subjects: 1- a group of healthy adults in whom the results of the test with cinacalcet will be compared with those of the standardized PTH suppression test with intravenous calcium loading; 2- a group of patients with proven primary hyperparathyroidism in whom the results of the test with cinacalcet will be compared with those obtained during the same test, in healthy controls.

Timeline

Start

2010-04

Primary completion

2013-02

Completion

2013-02

Publications

• Results Cailleux A, Vuillermet P, Basuyau JP, Menard JF, Lefebvre H, Kuhn JM, Prevost G. A step towards cinacalcet testing for the diagnosis of primary hyperparathyroidism: comparison with the standardized intravenous calcium loading. A pilot study. Clin Endocrinol (Oxf). 2015 May;82(5):663-9. doi: 10.1111/cen.12729. Epub 2015 Mar 5.

Drugs

Indications

No indication recorded.