drugset / Trial / NCT01103336

Preventive Effect of the PRetreatment With Intravenous Nicorandil on Contrast-Induced Nephropathy in Patients With RenaL Dysfunction UndEergoing Coronary Angiography (PRINCIPLE Study)

NCT01103336

Phase 4 Completed 173 enrolled Yonsei University GE Healthcare · collab
RandomizedParallel-groupOpen-labelPrevention

Summary

Renal hypoxia plays an important role in the development of contrast-induced nephropathy. The purpose of the PRINCIPLE study is to investigate the effect of pretreatment with intravenous nicorandil on the incidence of contrast-induced nephropathy in patients with renal insufficiency undergoing coronary angiography.

Timeline

Start
2010-03
Primary completion
2011-06
Completion
2011-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Nicorandil Other / unclassified 12 mg Intravenous