drugset / Trial / NCT01106469
Pharmacokinetics (PK) and Pharmacodynamics (PD) Study of Single and Multiple Ascending Doses of JNJ-41443532 in Healthy Male Participants
RandomizedCrossoverDouble-blindBasic science
Summary
The purpose of this study is to investigate the safety, tolerability, food effect as well as the pharmacokinetics (how the drug is absorbed in the body, how it is distributed within the body and how it is removed from the body over time) and pharmacodynamics (the effects of the drug) of single and multiple ascending doses of JNJ-41443532 in healthy male participants.
Timeline
- Start
- 2010-02
- Primary completion
- —
- Completion
- 2010-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | JNJ-41443532 | Small molecule | 25 mg | Oral |
| Subject | JNJ-41443532 | Small molecule | 100 mg | Oral |
| Subject | JNJ-41443532 | Small molecule | 250 mg | Oral |
| Subject | JNJ-41443532 | Small molecule | 500 mg | Oral |
| Subject | JNJ-41443532 | Small molecule | 1000 mg | Oral |
| Subject | JNJ-41443532 | Small molecule | 1500 mg | Oral |
Indications
No indication recorded.