Mucosal Response in Immunocompromised Host

Phase 4 Completed 51 enrolled Leiden University Medical Center Crucell B.V., Leiden, the Netherlands · collab

Non-randomizedParallel-groupOpen-labelPrevention

Summary

The aim of this study is to verify whether vaccination with Dukoral® (SBL Vaccines) induces an immune response in renal transplant recipients on prednisolone in combination with either a calcineurin inhibitor CNI) or mycophenolate mofetil (MMF).

Timeline

Start: 2010-04
Primary completion: 2015-03
Completion: 2015-03

Publications

Jonker EFF, Uijlings MAC, Visser LG, Soonawala D. Comparison of the immunogenicity of Dukoral(R) oral cholera vaccine between renal transplant recipients on either a calcineurin inhibitor or mycophenolate - A controlled trial. Vaccine. 2019 May 21;37(23):3133-3139. doi: 10.1016/j.vaccine.2019.04.010. Epub 2019 Apr 24.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Shanchol	Vaccine	3 ml	—
Subject	Shanchol	Vaccine	5.6 g	—

Indications

No indication recorded.