drugset / Trial / NCT01113502

Eltrombopag in Elderly Acute Myelogenous Leukemia (AML)

NCT01113502

Phase 1/2 Terminated 44 enrolled Abramson Cancer Center at Penn Medicine
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This is a phase I/II open label study being conducted to evaluate the overall safety and initial effectiveness of an investigational drug, Eltrombopag in patients who are 60 years of age and older and who have Acute Myelogenous Leukemia (AML). Eltrombopag is an investigational drug, which means it has not been approved by the U.S. Food and Drug Administration (FDA) for use in this type of disease. Approximately 35 people will be enrolled on this study at the University of Pennsylvania

Timeline

Start
2010-06
Primary completion
2013-03-14
Completion
2015-11-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Eltrombopag Small molecule 50 mg Oral
Subject Eltrombopag Small molecule 100 mg Oral
Subject Eltrombopag Small molecule 200 mg Oral
Subject Eltrombopag Small molecule 300 mg Oral