Impact of the Inhibitors of Tyrosine Kinase on the Male Fertility

Summary

Evaluate the possible deleterious effects of tyrosine kinase inhibitors on sperm concentration, after 6 months of therapy, which corresponds to 2 cycles of spermatogenesis and on the sperm nuclear integrity. The main comparison criterion will be the mean difference in sperm concentration before and after the 6 month treatment.

Timeline

Start

2008-10

Primary completion

2009-05

Completion

2009-05

Drugs

Indications