Antibiotic Prophylaxis for Early Ventilator-associated Pneumonia in Neurological Patients

Summary

This study seeks to assess whether coma patients really benefit from the use of antibiotics as a prophylactic for reducing the incidence of early ventilator-associated pneumonia in this population group. For this we consider the use of ampicillin sulbactam antibiotic which has a low ability to induce resistance, efficacy and safety observed during the time that has been used, even in patients with neurosurgical pathology, and to be broadly available in our environment. Our hypothesis is that neurological patients in coma state, requiring mechanical ventilation, the application of antibiotic prophylaxis compared with placebo reduces the incidence of early ventilator-associated pneumonia.

Timeline

Start

2011-03

Primary completion

2011-03

Completion

2011-03

Outcome

Outcome not reported

Stopped (Business): “He could not be started due to lack of funds”

Drugs

Indications

No indication recorded.