drugset / Trial / NCT01129102
Efficacy and Safety Study of NPC-01 to Treat Dysmenorrhea
RandomizedParallel-groupTriple-blindTreatment
Summary
The purpose of this study is to determine whether NPC-01 is effective in the treatment of dysmenorrhea.
Timeline
- Start
- 2010-05
- Primary completion
- 2011-04
- Completion
- 2011-04
Outcome
Met primary endpoint
paper total dysmenorrhea score and visual analog scale score after the treatment were significantly higher in the NPC-01 group than in the placebo group. PMID 27717552 ↗
Publications
- Schroll JB, Black AY, Farquhar C, Chen I. Combined oral contraceptive pill for primary dysmenorrhoea. Cochrane Database Syst Rev. 2023 Jul 31;7(7):CD002120. doi: 10.1002/14651858.CD002120.pub4.
- Harada T, Momoeda M. Evaluation of an ultra-low-dose oral contraceptive for dysmenorrhea: a placebo-controlled, double-blind, randomized trial. Fertil Steril. 2016 Dec;106(7):1807-1814. doi: 10.1016/j.fertnstert.2016.08.051. Epub 2016 Oct 4.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Norethindrone | Unknown | 1 mg | Oral |
| Subject | ethinyl estradiol | Small molecule | 0.02 mg | Oral |
| Subject | ethinyl estradiol | Small molecule | 0.035 mg | Oral |