The Use of DHEA in Women With Premature Ovarian Failure

Phase 0 Withdrawn Virginia Center for Reproductive Medicine

Non-randomizedSingle-groupOpen-labelTreatment

Summary

DHEA supplementation has been used in women with infertility and diminished ovarian reserve. There is a small report in 5 women with POF that benefited from the use of DHEA over several months. The investigators aim to evaluate further the use of DHEA in women with Premature ovarian failure (POF).

Timeline

Start: 2010-05
Primary completion: 2013-01
Completion: 2013-01

Outcome

Outcome not reported

Stopped (Enrollment): “very poor patient recruitement”

Publications

Background Mamas L, Mamas E. Dehydroepiandrosterone supplementation in assisted reproduction: rationale and results. Curr Opin Obstet Gynecol. 2009 Aug;21(4):306-8. doi: 10.1097/gco.0b013e32832e0785.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	DHEA	Unknown	25 mg	—