Combination Treatment for Posttraumatic Stress Disorder (PTSD) After the World Trade Center (WTC) Attack

Phase 4 Completed 37 enrolled Research Foundation for Mental Hygiene, Inc. National Institute of Mental Health (NIMH) · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

This randomized controlled trial evaluates efficacy of combined prolonged exposure (PE) and the selective serotonin reuptake inhibitor (SSRI) paroxetine in the treatment of survivors of the World Trade Center (WTC) attacks.

Timeline

Start: 2004-03
Primary completion: 2010-02
Completion: 2010-02

Publications

Schneier FR, Neria Y, Pavlicova M, Hembree E, Suh EJ, Amsel L, Marshall RD. Combined prolonged exposure therapy and paroxetine for PTSD related to the World Trade Center attack: a randomized controlled trial. Am J Psychiatry. 2012 Jan;169(1):80-8. doi: 10.1176/appi.ajp.2011.11020321. Epub 2011 Sep 9.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Paroxetine	Small molecule	12.5 mg	—
Subject	Paroxetine	Small molecule	50 mg	—

Combination Treatment for Posttraumatic Stress Disorder (PTSD) After the World Trade Center (WTC) Attack

Summary

Timeline

Publications

Drugs

Indications