drugset / Trial / NCT01131078

A Study of Avastin (Bevacizumab) in Combination Chemotherapy in Patients With Metastatic Cancer of the Colon or Rectum

NCT01131078 ↗

Phase 2 Completed 306 enrolled Hoffmann-La Roche
RandomizedParallel-groupOpen-labelTreatment

Summary

A study of Avastin (bevacizumab) in combination chemotherapy in patients with metastatic cancer of the colon or rectum. The anticipated time on study treatment is until disease progression.

Timeline

Start
2005-06
Primary completion
2012-11
Completion
2012-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 7.5 mg/kg Intravenous
Subject Capecitabine Small molecule 650 mg/m2 Oral
Subject Capecitabine Small molecule 1000 mg/m2 Oral
Subject Capecitabine Small molecule 1250 mg/m2 Oral
Subject Irinotecan Small molecule 240 mg/m2 Intravenous

Indications