drugset / Trial / NCT01131429

A Chinese Randomized Crossover Study of Erlotinib Versus Docetaxel/Cisplatin in Previously Untreated Stage IIIB/IV Lung Adenocarcinoma With EGFR Mutations

NCT01131429

Phase 2 Unknown 60 enrolled Chinese PLA General Hospital
RandomizedCrossoverOpen-labelTreatment

Summary

Objective: the objective of this study in china is to clarify, whether the overall survival is different between previously untreated stage IIIB/IV lung adenocarcinoma with EGFR mutations receiving first-line erlotinib plus second-line docetaxel/cisplatin and those receiving first-line docetaxel/cisplatin plus second-line erlotinib .

Timeline

Start
2010-06
Primary completion
2013-06
Completion
2015-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cisplatin Other / unclassified 75 mg/m2
Comparator Docetaxel Small molecule 75 mg/m2
Comparator Erlotinib Small molecule 150 mg Oral