Safety Study of RP-1127 (Glyburide for Injection) in Healthy Volunteers

Summary

The primary objective of this study is to evaluate the safety and tolerability of different dose levels of glyburide for injection, administered as a bolus dose followed by a 3-day continuous infusion. The secondary objectives are to assess the pharmacokinetics (PK) of glyburide and blood glucose and serum insulin pharmacodynamic (PD) responses to glyburide.

Timeline

Start

2010-01-07

Primary completion

2010-05-07

Completion

2010-05-07

Drugs

Indications