drugset / Trial / NCT01134185
Evaluation of Prucalopride in Subjects With Moderate and Severe Hepatic Impairment
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This is a single centre, open-label phase I trial to investigate the effects of moderate to severe hepatic impairment on the pharmacokinetics of prucalopride in comparison with healthy volunteers. Furthermore the short-term safety and tolerability of a single dose of prucalopride will be assessed.
Timeline
- Start
- 2010-05
- Primary completion
- 2011-02
- Completion
- 2011-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Prucalopride | Small molecule | 2 mg | Oral |
Indications
No indication recorded.