drugset / Trial / NCT01135472
Plasm Gastrin Concentrations in Response to Nexium Administration in Healthy Volunteers
RandomizedParallel-groupOpen-labelBasic science
Summary
This dose response study is proposed to explore the extent to which Nexium increases endogenous gastrin concentrations and to assess whether Nexium treatment may be useful in the setting of islet cell transplantation for type 1 diabetes to expand islet cells in vivo after transplant.
Timeline
- Start
- 2010-03
- Primary completion
- 2012-04
- Completion
- 2012-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Esomeprazole | Small molecule | 40 mg | — |
| Subject | Esomeprazole | Small molecule | 80 mg | — |
Indications
No indication recorded.