drugset / Trial / NCT01135472

Plasm Gastrin Concentrations in Response to Nexium Administration in Healthy Volunteers

NCT01135472

Phase 1 Completed 10 enrolled City of Hope Medical Center
RandomizedParallel-groupOpen-labelBasic science

Summary

This dose response study is proposed to explore the extent to which Nexium increases endogenous gastrin concentrations and to assess whether Nexium treatment may be useful in the setting of islet cell transplantation for type 1 diabetes to expand islet cells in vivo after transplant.

Timeline

Start
2010-03
Primary completion
2012-04
Completion
2012-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Esomeprazole Small molecule 40 mg
Subject Esomeprazole Small molecule 80 mg

Indications

No indication recorded.