drugset / Trial / NCT01140399

REWORD-HF REverse WOrsening Renal Function in Decompensated Heart Failure

NCT01140399

RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to determine whether in patients with acute decompensated congestive heart failure and the cardiorenal syndrome, i.e. a state in which therapy directed to improve symptoms is limited by further worsening renal function, fluid removal by ultrafiltration is superior to different pharmacological approaches in acutely relieving congestion and preventing further deterioration in renal function and whether it results in longer admission-free survival 90 days after enrolment

Timeline

Start
2011-02
Primary completion
2011-06
Completion
2017-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dopamine Small molecule 3 ug/kg Intravenous
Comparator Furosemide Other / unclassified 20 mg Intravenous

Indications