drugset / Trial / NCT01140399
REWORD-HF REverse WOrsening Renal Function in Decompensated Heart Failure
Phase 4
Terminated
10 enrolled
Niguarda Hospital
Associazione Nazionale Medici Cardiologi Ospedalieri · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to determine whether in patients with acute decompensated congestive heart failure and the cardiorenal syndrome, i.e. a state in which therapy directed to improve symptoms is limited by further worsening renal function, fluid removal by ultrafiltration is superior to different pharmacological approaches in acutely relieving congestion and preventing further deterioration in renal function and whether it results in longer admission-free survival 90 days after enrolment
Timeline
- Start
- 2011-02
- Primary completion
- 2011-06
- Completion
- 2017-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dopamine | Small molecule | 3 ug/kg | Intravenous |
| Comparator | Furosemide | Other / unclassified | 20 mg | Intravenous |