drugset / Trial / NCT01141036
Propofol Versus Midazolam for Upper Endoscopy in Cirrhotic Patients
RandomizedParallel-groupSingle-blindSupportive care
Summary
Upper GI endoscopy is often performed in patients with chronic liver disease to screen for esophageal and gastric varices. The purpose of this study is to compare propofol to midazolam for sedation in patients with chronic liver disease undergoing diagnostic upper GI endoscopy.
Timeline
- Start
- 2008-07
- Primary completion
- 2009-01
- Completion
- 2009-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Midazolam | Small molecule | 0.5 mg | — |
| Comparator | Midazolam | Small molecule | 1 mg | — |
| Comparator | Propofol | Small molecule | 10 mg | Intravenous |
| Comparator | Propofol | Small molecule | 20 mg | Intravenous |