drugset

drugset / Trial / NCT01142258

Trazodone for Sleep Disorders in Alzheimer's Disease

NCT01142258 ↗

Phase 3 Completed 40 enrolled Brasilia University Hospital Universidade Federal do Paraná · collab

RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to determine whether trazodone is effective in the treatment of sleep disorders in Alzheimer's disease (AD).

Timeline

Start: 2010-03
Primary completion: 2012-04
Completion: 2012-08

Publications

McCleery J, Sharpley AL. Pharmacotherapies for sleep disturbances in dementia. Cochrane Database Syst Rev. 2020 Nov 15;11(11):CD009178. doi: 10.1002/14651858.CD009178.pub4.
Camargos EF, Louzada LL, Quintas JL, Naves JO, Louzada FM, Nobrega OT. Trazodone improves sleep parameters in Alzheimer disease patients: a randomized, double-blind, and placebo-controlled study. Am J Geriatr Psychiatry. 2014 Dec;22(12):1565-74. doi: 10.1016/j.jagp.2013.12.174. Epub 2014 Jan 4.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Trazodone	Small molecule	50 mg	—

Indications