drugset / Trial / NCT01142284
Evaluation of Concomitant Administration of Cilostazol and Probucol on Biomarkers, Endothelial Function and Safety
RandomizedParallel-groupOpen-labelTreatment
Summary
Based upon evidence of efficacy and safety of both cilostazol and probucol administration in independent randomized controlled trials in PAD and CAD, the present trial seeks to investigate the effect of concomitant administration of cilostazol and probucol on FMD compared to each drug individually, as well as to evaluate biomarker measures and safety indices in this context.
Timeline
- Start
- 2010-05-19
- Primary completion
- 2012-11-29
- Completion
- 2012-12-18
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cilostazol | Small molecule | 100 mg | Oral |
| Subject | Probucol | Small molecule | 250 mg | Oral |