drugset / Trial / NCT01142284

Evaluation of Concomitant Administration of Cilostazol and Probucol on Biomarkers, Endothelial Function and Safety

NCT01142284

Phase 2 Completed 80 enrolled Korea Otsuka Pharmaceutical Co., Ltd.
RandomizedParallel-groupOpen-labelTreatment

Summary

Based upon evidence of efficacy and safety of both cilostazol and probucol administration in independent randomized controlled trials in PAD and CAD, the present trial seeks to investigate the effect of concomitant administration of cilostazol and probucol on FMD compared to each drug individually, as well as to evaluate biomarker measures and safety indices in this context.

Timeline

Start
2010-05-19
Primary completion
2012-11-29
Completion
2012-12-18

Drugs

EvaluationDrugModalityDoseRoute
Subject Cilostazol Small molecule 100 mg Oral
Subject Probucol Small molecule 250 mg Oral