drugset / Trial / NCT01144000
Daptomycin With Rifampin for Treatment of Staphylococcal Prosthetic Joint Infection
Phase 2
Unknown
60 enrolled
Andrej Trampuz
Kantonsspital Liestal · collabSchulthess Klinik · collabUniversity of Lausanne Hospitals · collab
NaSingle-groupOpen-labelTreatment
Summary
To determine the outcome and safety of a combined antimicrobial treatment involving daptomycin and surgical approach involving retention or short-interval two-stage exchange of the implant. Patients with hip, knee and shoulder Prosthetic Joint Infection (PJI) caused by methicillin-susceptible and methicillin-resistant staphylococci will be included and followed during 2 years.
Timeline
- Start
- 2012-06
- Primary completion
- 2014-06
- Completion
- 2016-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Daptomycin | Other / unclassified | 10 mg/kg | Intravenous |