drugset / Trial / NCT01144143
Treatment Of Knee Osteoarthritis With Intra-Articular Infliximab
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to determine if an anti-inflammatory drug, called infliximab, will reduce inflammation in the synovial lining in patients with an early stage of osteoarthritis of the knee. It will also help determine if the study medication decreases the accumulation of synovial fluid and prevents cartilage breakdown.
Timeline
- Start
- 2007-07
- Primary completion
- 2010-12
- Completion
- 2011-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Infliximab | Monoclonal antibody | 100 mg | Other |
| Comparator | Methylprednisolone | Other / unclassified | 80 mg | Other |