Dapsone for Acute Ischemia Stroke Study

Phase 2/3 Unknown 300 enrolled Cidat, S.A. de C.V. El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez · collab

RandomizedParallel-groupTriple-blindPrevention

Summary

The main purpose of the study is to get information about the safety and efficacy of treatment with Dapsone to prevent the disability after ischemic Stroke, in patients diagnosed with anterior territory brain infarct.

Timeline

Start: 2009-07
Primary completion: 2010-08
Completion: 2010-11

Outcome

Met primary endpoint

paper Favorable scores were achieved for treated patients by all different measures; NIHSS (p=0.032), Barthel (p=0.049) PMID 17509235 ↗

Publications

Results Nader-Kawachi J, Gongora-Rivera F, Santos-Zambrano J, Calzada P, Rios C. Neuroprotective effect of dapsone in patients with acute ischemic stroke: a pilot study. Neurol Res. 2007 Apr;29(3):331-4. doi: 10.1179/016164107X159234.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Dapsone	Small molecule	250 mg	Intravenous