A Multi-Center Clinical Trial To Evaluate Chinese Herbal Medicines in the Treatment of Severe Hand-foot-mouth Disease

Unknown 390 enrolled Beijing YouAn Hospital Beijing University of Chinese Medicine · collab China Academy of Chinese Medical Sciences · collab State Administration of Traditional Chinese Medicine of the People's Republic of China · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

The aim of this study is to evaluate the effectiveness and safety of Chinese herbal medicines for severe hand-foot-mouth disease.

Timeline

Start: 2010-05
Primary completion: 2010-08
Completion: —

Outcome

Met primary endpoint

paper The temperature decreased half-life time was 40.4 h in the WM therapy group, significantly longer than 27.2 h in the CM plus WM therapy group (P<0.01). PMID 27392481 ↗

Publications

Li XH, Li SJ, Xu Y, Wei D, Shi QS, Zhu QX, Yang T, Ding JB, Tian YM, Huang JH, Wang K, Wen T, Zhang X. Effect of integrated Chinese and Western medicine therapy on severe hand, foot and mouth disease: A prospective, randomized, controlled trial. Chin J Integr Med. 2017 Dec;23(12):887-892. doi: 10.1007/s11655-016-2504-3. Epub 2016 Jul 9.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Reduning	Traditional medicine (herbal / TCM)	—	—