drugset

drugset / Trial / NCT01147276

Vildagliptin and the Glucagon Response to Hypoglycemia in Type 1 Diabetes

NCT01147276 ↗

Phase 4 Completed 28 enrolled Lund University

RandomizedCrossoverDouble-blindBasic science

Summary

The study examines whether DPP-4 inhibition by vildagliptin affects the glucagon counterregulatory response to hypoglycemia in type 1 diabetes.

Timeline

Start: 2010-09
Primary completion: 2011-09
Completion: 2011-12

Publications

Farngren J, Persson M, Schweizer A, Foley JE, Ahren B. Vildagliptin reduces glucagon during hyperglycemia and sustains glucagon counterregulation during hypoglycemia in type 1 diabetes. J Clin Endocrinol Metab. 2012 Oct;97(10):3799-806. doi: 10.1210/jc.2012-2332. Epub 2012 Aug 1.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Vildagliptin	Other / unclassified	50 mg	—

Indications