A Safety and Pharmacokinetic Study of Paliperidone Palmitate in Patients With Schizophrenia

Summary

The purpose of this study is to evaluate the long term safety of flexible doses (50 to 150 mg equivalent) of paliperidone palmitate in the treatment of patients with schizophrenia and to document the pharmacokinetics of paliperidone following fixed multiple intramuscular injections of paliperidone palmitate 150 mg eq.

Timeline

Start

2007-09

Primary completion

2009-06

Completion

2009-06

Publications

• Coppola D, Liu Y, Gopal S, Remmerie B, Samtani MN, Hough DW, Nuamah I, Sulaiman A, Pandina G. A one-year prospective study of the safety, tolerability and pharmacokinetics of the highest available dose of paliperidone palmitate in patients with schizophrenia. BMC Psychiatry. 2012 Mar 28;12:26. doi: 10.1186/1471-244X-12-26.

Drugs

Indications