drugset / Trial / NCT01150890

Brodalumab (AMG 827) in Adults With Moderate to Severe Crohn's Disease

NCT01150890

Phase 2 Terminated 130 enrolled Amgen
RandomizedParallel-groupDouble-blindTreatment

Summary

The study will examine the safety and effectiveness of brodalumab for the treatment of moderate to severe Crohn's disease. Participants will randomly assigned to receive either brodalumab or placebo (a lookalike liquid that doesn't have any drug in it) and neither the doctor nor the patient will know what treatment is being given.

Timeline

Start
2010-11-09
Primary completion
2011-10-15
Completion
2011-10-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Brodalumab Monoclonal antibody 210 mg Intravenous
Subject Brodalumab Monoclonal antibody 350 mg Intravenous
Subject Brodalumab Monoclonal antibody 700 mg Intravenous

Indications