drugset / Trial / NCT01151046

Trial of Exemestane +/- MM-121 in Postmenopausal Women With Locally Advanced or Metastatic Estrogen Receptor Positive and/or Progesterone Receptor Positive Her2 Negative Breast Cancer

NCT01151046

Phase 2 Completed 118 enrolled Merrimack Pharmaceuticals
RandomizedParallel-groupTriple-blindTreatment

Summary

To determine whether the combination MM-121 + Exemestane in ER+ and/or PR+ breast cancer patients is more effective than Exemestane alone

Timeline

Start
2010-06
Primary completion
2014-06
Completion
2014-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Exemestane Small molecule 25 mg Oral
Subject Seribantumab Monoclonal antibody 20 mg/kg Intravenous