drugset / Trial / NCT01159054

Novel Pathways to Manage Inflammation and Atherosclerosis in Dialysis Patients: Role of Nicotinic Acid

NCT01159054

Terminated 22 enrolled Brigham and Women's Hospital
NaSingle-groupOpen-labelTreatment

Summary

Patients with kidney failure on hemodialysis have an extremely high rate of cardiovascular disease including atherosclerotic cardiovascular disease. This, at least in part, is due to the chronic inflammatory status usually seen in these patients. Here we try to see if treatment with extended release nicotinic acid (Niaspan) can reduce their overall inflammatory burden (in general) and the atherosclerotic plaque inflammation (in particular).

Timeline

Start
2010-07
Primary completion
2014-12
Completion
2014-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Niacin Small molecule 1500 mg
Subject Niacin Small molecule 2000 mg

Indications