Pharmacodynamic and Pharmacokinetic Effects of Insulin Glulisine in Obese Subjects With Type 2 Diabetes After a Standard Meal in Comparison to Insulin Aspart

Summary

Primary Objective: * To assess the effect of insulin glulisine on the post-prandial plasma glucose excursion during the first hour after a standard meal in comparison to insulin aspart in obese subjects with type 2 diabetes. Secondary Objectives: Pharmacodynamic objectives: * To assess the effect of insulin glulisine on the postprandial plasma glucose excursion during 6 hours after a standard meal in comparison to insulin aspart. Pharmacokinetic objective: * To assess post-prandial plasma insulin excursion after a standard meal, in each treatment groups Safety objective: * To assess the safety of insulin glulisine in comparison to insulin aspart

Timeline

Start

2007-09

Primary completion

2008-04

Completion

2008-04

Drugs

Indications