drugset / Trial / NCT01160822
To Determine the Safety, Tolerability, Pharmacokinetics and Effect on Pain of a Single Intra-articular Administration of Canakinumab in Patients With Osteoarthritis in the Knee
RandomizedParallel-groupTriple-blindTreatment
Summary
The purpose of this study was to determine whether, in patients with mild to moderate knee osteoarthritis, canakinumab is safe and tolerable when injected intra-articularly.
Timeline
- Start
- 2010-04
- Primary completion
- 2011-07
- Completion
- 2011-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Canakinumab | Monoclonal antibody | 150 mg | Other |
| Subject | Canakinumab | Monoclonal antibody | 300 mg | Other |
| Subject | Canakinumab | Monoclonal antibody | 600 mg | Other |
| Comparator | Naproxen | Small molecule | 500 mg | Oral |