drugset / Trial / NCT01162239
Maintaining Nonsmoking
Phase 3
Completed
216 enrolled
University of California, San Francisco
National Institute on Drug Abuse (NIDA) · collabPfizer · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The research is based on a chronic disorder model of cigarette smoking which suggests that long-term treatment targeted to prevent relapse may be useful. Based on this model, the investigators have developed a relapse prevention treatment to intervene on five areas important in relapse prevention, including fluctuating motivation, depression, withdrawal, weight gain, and social support. This treatment protocol has produced high long-term abstinence rates when implemented in a clinical research setting. The current study will evaluate the treatment model when implemented in a medical outpatient setting.
Timeline
- Start
- 2010-05
- Primary completion
- 2016-06
- Completion
- 2016-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Varenicline | Small molecule | 1 mg | — |