drugset / Trial / NCT01162967
Clinical Trial For The Treatment Of Chronic Chagas Disease With Posaconazole And Benznidazole
Phase 2
Completed
78 enrolled
Hospital Universitari Vall d'Hebron Research Institute
Hospital Vall d'Hebron · collabInternational Health Unit Metropolitana Nord. Santa Coloma. · collabTropical Medicine and International Health Unit Drassanes. Barcelona · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The investigators propose the evaluation of posaconazole and benznidazole in humans for the treatment of Chagas disease chronical infection. Exploratory trial of posaconazole antiparasitic activity against Trypanosoma cruzi.
Timeline
- Start
- 2010-09
- Primary completion
- 2012-12
- Completion
- 2013-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Benznidazole | Small molecule | 150 mg | — |
| Subject | Posaconazole | Small molecule | 100 mg | — |
| Subject | Posaconazole | Small molecule | 400 mg | — |