drugset / Trial / NCT01163487
Metabolic Reprogramming Therapy for Treatment of Recurrent Head and Neck Cancers
NaSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to study the effect of the drug DCA (dichloroacetate) on recurrent head and neck cancers. Part of this study will also use EF5 PET scan to study tumor hypoxia.
Timeline
- Start
- 2010-08
- Primary completion
- 2015-02
- Completion
- 2016-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | DICHLOROACETIC ACID | Small molecule | 25 mg/kg | Oral |
| Subject | DICHLOROACETIC ACID | Small molecule | 37.5 mg/kg | Oral |
| Subject | DICHLOROACETIC ACID | Small molecule | 50 mg/kg | Oral |