drugset / Trial / NCT01165294

The Effect of Ketamine on Attentiveness

NCT01165294

RandomizedCrossoverDouble-blindBasic science

Summary

The objective of this study is to develop an exploratory design for future Proof-of-Concept trials which reliably and accurately measure the central nervous system (CNS) effects of potentially new drugs that oppose the effects of ketamine at a subanesthetic dose level given to healthy volunteers. A functional magnetic resonance imaging (fMRI) and electroencephalogram (EEG) performed simultaneously during a ketamine challenge will register the effects triggered by Ketamine.

Timeline

Start
2009-10
Primary completion
Completion
2010-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketamine Small molecule 0.015625 mg/kg Intravenous

Indications