drugset / Trial / NCT01166126

Temsirolimus/AZD 6244 for Treatment-naive With BRAF Mutant Unresectable Stage IV

NCT01166126

Phase 2 Terminated 4 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to find out how often two investigational drugs that are given together will shrink the patient's tumor and how well they will prolong the time it takes their tumor to grow. The investigators also wish to find out how they affect certain substances in the patient's tumor and in their blood important for tumor growth. The combination of these drugs is experimental, and has not been proven to help treat melanoma

Timeline

Start
2010-10
Primary completion
2012-06
Completion
2012-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Selumetinib Small molecule Oral
Subject Temsirolimus Small molecule Intravenous

Indications