drugset / Trial / NCT01170117
Olanzapine Versus Placebo for Outpatients With Anorexia Nervosa
Completed
152 enrolled
New York State Psychiatric Institute
Johns Hopkins University · collabNational Institute of Mental Health (NIMH) · collabUniversity of Pittsburgh · collabUniversity of Toronto · collabWeill Medical College of Cornell University · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Anorexia Nervosa (AN) is a serious illness associated with substantial morbidity and mortality. Weight restoration is a treatment priority, and better treatments are needed.
Timeline
- Start
- 2010-08
- Primary completion
- 2016-06
- Completion
- 2017-06
Publications
- Background Bissada H, Tasca GA, Barber AM, Bradwejn J. Olanzapine in the treatment of low body weight and obsessive thinking in women with anorexia nervosa: a randomized, double-blind, placebo-controlled trial. Am J Psychiatry. 2008 Oct;165(10):1281-8. doi: 10.1176/appi.ajp.2008.07121900. Epub 2008 Jun 16.
- Attia E, Steinglass JE, Walsh BT, Wang Y, Wu P, Schreyer C, Wildes J, Yilmaz Z, Guarda AS, Kaplan AS, Marcus MD. Olanzapine Versus Placebo in Adult Outpatients With Anorexia Nervosa: A Randomized Clinical Trial. Am J Psychiatry. 2019 Jun 1;176(6):449-456. doi: 10.1176/appi.ajp.2018.18101125. Epub 2019 Jan 18.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Olanzapine | Small molecule | 10 mg | — |