Studying the Effects of Sibutramine on Eating Behavior

Summary

Obesity is a major public health concern, and the search for useful pharmacologic interventions is ongoing. This study aims to develop a comprehensive series of assessments to directly assess eating behavior, cognitive functioning, and psychological functioning under sibutramine and placebo conditions.

Timeline

Start

2009-02

Primary completion

2010-10

Completion

2010-10

Outcome

Met primary endpoint

Stopped: “Terminated due to sibutramine being withdrawn from the market.”

registry analysis (superiority test); Sibutramine vs Placebo; p <0.004; paired sample t-test, two tailed NCT01170364 ↗

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Sibutramine	Small molecule	15 mg	—

Indications