REsPonse to Interferon-Alpha in InterfeRon-β Neutralizing Antibody Positive Multiple Sclerosis Patients

Phase 2 Completed 10 enrolled Melinda Magyari University of Copenhagen · collab

Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of the study is to determine if Interferon-alfa is effective and safe in multiple sclerosis patients who developed neutralizing antibodies for Interferon-beta.

Timeline

Start: 2010-07
Primary completion: 2011-06
Completion: 2011-08

Publications

Magyari M, Bach Sondergaard H, Sellebjerg F, Soelberg Sorensen P. Preserved in vivo response to interferon-alpha in multiple sclerosis patients with neutralising antibodies against interferon-beta (REPAIR study). Mult Scler Relat Disord. 2013 Apr;2(2):141-6. doi: 10.1016/j.msard.2012.10.001. Epub 2012 Dec 11.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Interferon-beta	Protein / enzyme biologic	—	—
Subject	Interferon-α	Protein / enzyme biologic	6e+06 iu	Subcutaneous

REsPonse to Interferon-Alpha in InterfeRon-β Neutralizing Antibody Positive Multiple Sclerosis Patients

Summary

Timeline

Publications

Drugs

Indications