drugset / Trial / NCT01171482
Comparison Study of Sorafenib and 5-fluorouracil/Mitomycin for Metastatic Hepatocellular Carcinoma
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The aim of this study is to compare the efficacy of sorafenib to 5-fluorouracil/mitomycin in HCC patients with pulmonary metastasis whose intrahepatic tumors has been controlled with locoregional therapies.
Timeline
- Start
- 2015-11
- Primary completion
- 2016-04
- Completion
- 2016-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Mitomycin C | Other / unclassified | 4 mg | Intravenous |
| Comparator | Sorafenib | Small molecule | 400 mg | Oral |
| Subject | fluorouracil | Small molecule | 15 mg/kg | Intravenous |