drugset / Trial / NCT01173939

Primary Prevention of Major Adverse Cardiac Events (MACE) With Standard and Intensive Statin Treatment in Patients With Diabetes: Survival and Cardiovascular Event Assessments

NCT01173939

Terminated 10000 enrolled Positive Trial Group
RandomizedSingle-groupOpen-labelPrevention

Summary

The study is being conducted to compare the effect of standard treatment (target LDL-C level: \<120 mg/dL (JASGL 2007 target level)) and intensive treatment (target LDL-C level: \<70 mg/dL) in the prevention of major adverse cardiac events (MACE) in hypercholesterolemia patients with concomitant type 2 diabetes and hypertension.

Timeline

Start
2010-07
Primary completion
2014-06
Completion

Drugs

EvaluationDrugModalityDoseRoute
Comparator Pravastatin Small molecule 5 mg Oral
Comparator Pravastatin Small molecule 10 mg Oral
Comparator Rosuvastatin Small molecule 5 mg Oral
Comparator Rosuvastatin Small molecule 10 mg Oral