drugset / Trial / NCT01173939
Primary Prevention of Major Adverse Cardiac Events (MACE) With Standard and Intensive Statin Treatment in Patients With Diabetes: Survival and Cardiovascular Event Assessments
RandomizedSingle-groupOpen-labelPrevention
Summary
The study is being conducted to compare the effect of standard treatment (target LDL-C level: \<120 mg/dL (JASGL 2007 target level)) and intensive treatment (target LDL-C level: \<70 mg/dL) in the prevention of major adverse cardiac events (MACE) in hypercholesterolemia patients with concomitant type 2 diabetes and hypertension.
Timeline
- Start
- 2010-07
- Primary completion
- 2014-06
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Pravastatin | Small molecule | 5 mg | Oral |
| Comparator | Pravastatin | Small molecule | 10 mg | Oral |
| Comparator | Rosuvastatin | Small molecule | 5 mg | Oral |
| Comparator | Rosuvastatin | Small molecule | 10 mg | Oral |