Omega 3 Fatty Acid Efficiency for Prevention of Atrial Fibrillation After Coronary Artery Bypass Grafting

Phase 3 Terminated 39 enrolled Meshalkin Research Institute of Pathology of Circulation

RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to evaluate efficacy of Polyunsaturated Fatty Acid for the prevention of Atrial Fibrillation and anti-inflammatory effects in patients after CABG surgery

Timeline

Start: 2010-08
Primary completion: 2012-12
Completion: 2013-08

Outcome

Outcome not reported

Stopped: “Interim analysis did not reveal of anticipated benefits of intervention”

Publications

Results Lomivorotov VV, Efremov SM, Pokushalov EA, Romanov AB, Ponomarev DN, Cherniavsky AM, Shilova AN, Karaskov AM, Lomivorotov VN. Randomized trial of fish oil infusion to prevent atrial fibrillation after cardiac surgery: data from an implantable continuous cardiac monitor. J Cardiothorac Vasc Anesth. 2014 Oct;28(5):1278-84. doi: 10.1053/j.jvca.2014.02.019. Epub 2014 Jul 11.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Omegaven	Other / unclassified	1 ml	Intravenous
Comparator	Omegaven	Other / unclassified	100 mg/kg	Intravenous