drugset
drugset / Trial / NCT01176708

Intact Liver Innervation and Glucose and Glucagon-like Peptide-1 (GLP-1) Induced Insulin Secretion

NCT01176708 ↗

Unknown 30 enrolled University Hospital, Gentofte, Copenhagen University of Copenhagen · collab
Non-randomizedParallel-groupOpen-labelBasic science

Summary

The aim of the study is to investigate the significance of intact nerve supply to the liver for the glucagon-like peptide-1 (GLP-1) induced insulin secretion. The hypothesis is that the effects of GLP-1 is transmitted through the GLP-1 receptor and that these effects involve sensory afferent neurons, probably primarily parasympathetic.

Timeline

Start
2009-07
Primary completion
2012-08
Completion
2012-12

Drugs

EvaluationDrugModalityDoseRoute
Background Vildagliptin Other / unclassified 50 mg —

Indications

No indication recorded.