drugset / Trial / NCT01177397

Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myeloma

NCT01177397

Phase 1/2 Completed 226 enrolled Celgene Corporation
NaSingle-groupOpen-labelTreatment

Summary

The main purpose of this first human study with CC-223 is to assess the safety and action of a new class of experimental drug (dual mTOR inhibitors) in patients with advanced tumors unresponsive to standard therapies and to determine the appropriate dose and tumor type for later-stage clinical trials.

Timeline

Start
2010-07-20
Primary completion
2016-11-15
Completion
2016-12-09

Drugs

EvaluationDrugModalityDoseRoute
Subject ONATASERTIB Small molecule 7.5 mg Oral