drugset / Trial / NCT01179724

Comparison of Proton Pump Inhibitor and H2 Receptor Blocker on Prevention of Bleeding From Iatrogenic Ulcer After Endoscopic Submucosal Dissection for Gastric Neoplasms: A Prospective Randomized Controlled Trial

NCT01179724

Unknown 206 enrolled Samsung Medical Center
RandomizedParallel-groupSingle-blindPrevention

Summary

after endoscopic submucosal dissection(ESD) of early gastric cancer, conventional proton pump(PPI) inhibitors and H2 receptor antagonists have a controversial effect on preventing bleeding from artificial ulcers. the aim of this study was to investigate whether a stronger acid suppression (high dose PPI) more effectively prevents bleeding after ESD

Timeline

Start
2009-07
Primary completion
2010-09
Completion
2010-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Pantoprazole Other / unclassified 40 mg Intravenous
Comparator curan Unknown 300 mg Intravenous

Indications