A Study of E6005 in Japanese Patients With Atopic Dermatitis

Phase 1/2 Completed 40 enrolled Organon and Co

RandomizedParallel-groupOpen-labelTreatment

Summary

The safety and pharmacokinetics of topical application with E6005 ointment compared to vehicle will be evaluated in Japanese male patients with atopic dermatitis. Additionally, the efficacy of topical application with E6005 ointment will be explored in Japanese male patients with atopic dermatitis.

Timeline

Start: 2010-09
Primary completion: 2012-12
Completion: 2012-12

Publications

Ohba F, Nomoto M, Hojo S, Akama H. Safety, tolerability and pharmacokinetics of a novel phosphodiesterase inhibitor, E6005 ointment, in healthy volunteers and in patients with atopic dermatitis. J Dermatolog Treat. 2016;27(3):241-6. doi: 10.3109/09546634.2015.1093587. Epub 2015 Nov 18.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	LOTAMILAST	Small molecule	0.01 %	Topical
Subject	LOTAMILAST	Small molecule	0.03 %	Topical
Subject	LOTAMILAST	Small molecule	0.1 %	Topical
Subject	LOTAMILAST	Small molecule	0.2 %	Topical

A Study of E6005 in Japanese Patients With Atopic Dermatitis

Summary

Timeline

Publications

Drugs

Indications