The Study of Exenatide Action on Vessel Function in Type 2 Diabetes and Prediabetes

Summary

The purpose of this investigation is to evaluate whether exenatide, a type 2 diabetes medication, will improve the function of the innermost part of the arterial wall called the endothelium after a fat-enriched meal and to determine how this occurs. The results of this study will help to determine and understand a novel action of this group of diabetes medications based on the action of naturally occuring gut substances called incretins. This may have a significant impact on cardiovascular health in patients with early and longstanding diabetes.

Timeline

Start

2010-08

Primary completion

2012-12

Completion

2012-12

Drugs

Indications